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VAV2抗原,癌基因VAV2抗原

更新時間:2024-12-04點擊次數(shù):235

Recombinant human VAV2   

Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN

濃度:1mg/ ml

來源:Recombinant Human

純度:≥95% SDS-PAGE

表達(dá)系統(tǒng):Escherichia coli

標(biāo)簽:His tag

蛋白長度:Full length protein

內(nèi)毒素水平:<1.000 Eu/µg

純化方法:HPLC

應(yīng)用:SDS-PAGE,Western blot,ELISA

Biological activity,immunology research

保存:-20℃

保質(zhì)期:1年

VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.



產(chǎn)品名稱:Rabbit Anti-VAV2  antibody

Rabbit Anti-VAV2  

別名:Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN.          

來源:Rabbit

克隆類型:Polyclonal

濃度:1mg/ml

亞型:IgG

應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng):(predicted: Human,Mouse,Rat,Pig,Cow,Dog)

理論分子量:97kDa

免疫原:KLH conjugated synthetic peptide derived from human VAV2

保存:-20
保質(zhì)期:1

 

單克隆抗體

產(chǎn)品名稱:Anti-VAV2 antibody

Mouse Anti-VAV2 

別名:Oncogene VAV2; Protein vav 2; VAV 2; Vav 2 oncogene; VAV2 oncogene; VAV2_HUMAN.  

來源:Mouse

克隆類型:Monoclonal

濃度:1mg/ml

亞型:IgG

應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng): Human

理論分子量:97kDa

免疫原:KLH conjugated synthetic peptide derived from human VAV2

保存:-20
保質(zhì)期:1

VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.


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